CBX2 Antibody - middle region
Product Specifications
CAS Number
9007-83-4
Gene Name
Chromobox homolog 2
Gene Aliases
M33, CDCA6, SRXY5
Gene ID
84733
Swiss Prot
Q14781
Accession Number
NP_005180
Reactivity
Human, Rat, Cow, Horse, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human CBX2
Target
CBX2 Contains 1 A.T hook DNA-binding domain and 1 chromo domain. CBX2 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Partner Proteins
KRTAP10-3; KRTAP10-1; KRTAP10-9; KRTAP10-7; RBMY1F; DHX57; KRTAP2-4; RBMY1A1; RNF2; BMI1; MDFI; SOX2; GTF2I; PHC2; CSNK2B; CSNK2A2; CSNK2A1; CENPE; PARP1; CCDC158; DIS3L2; HIST4H4; CBX2; PARP12; RNF213; ZKSCAN7; DCAF6; KDM3A; MYCBP2; ANKRD26; PSME3; TRANK
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
SDSDPDSASPPSTGQNPSVSVQTSQDWKPTRSLIEHVFVTDVTANLITVT
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 86%; Horse: 93%; Human: 100%; Pig: 79%; Rat: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
56kDa
Protein Length
532
NCBI Gene Symbol
CBX2
Host or Source
Rabbit
Protein Name
Chromobox protein homolog 2
Gene Name URL
CBX2
Nucleotide Accession Number
NM_005189
Curated Selection
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