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ACD Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Adrenocortical dysplasia homolog (mouse)

Gene Aliases

PIP1, PTOP, TPP1, TINT1

Gene ID

65057

Swiss Prot

Q96AP0

Accession Number

NP_001075955

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human ACD

Target

ACD is a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere.This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.

Partner Proteins

TINF2; ANXA8L1; POT1; USP7; CUL5; ZNF790; PAGE2; APOBEC3F; NUDCD2; LRRC25; TRIM15; AFAP1L2; TBC1D10A; PDLIM2; RBKS; ANKMY2; PGM2; SBDS; LGALSL; DBNL; AIPL1; NCDN; STIP1; TOMM34; NUDC; TRIM16; TUBB4B; STUB1; FAM131B; BAG3; RECQL4; EIF3G; FKBP6; YWHAE; TUBB

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SSQPSPAICSAPATLTPRSPHASRTPSSPLQSCTPSLSPRSHVPSPHQAL

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

58kDa

Protein Length

544

NCBI Gene Symbol

ACD

Host or Source

Rabbit

Protein Name

Adrenocortical dysplasia protein homolog

Gene Name URL

ACD

Nucleotide Accession Number

NM_001082486

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