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IKZF2 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

IKAROS family zinc finger 2 (Helios)

Gene Aliases

ANF1A2, HELIOS, ZNF1A2, ZNFN1A2

Gene ID

22807

Swiss Prot

Q9UKS7

Accession Number

NP_057344

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human IKZF2

Target

IKZF2 is associates with Ikaros at centromeric heterochromatin.This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Partner Proteins

LONRF1; CTBP2; AQP1; CTBP1; UBC; HDAC1; HOXA1; NOTCH1; IKZF4; IKZF5; IKZF2; IKZF1; IKZF3; SIN3A; SIN3B; HDAC5; HDAC2; CHD4; HDAC4

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EREASPSNSCLDSTDSESSHDDHQSYQGHPALNPKRKQSPAYMKEDVKAL

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Yeast: 82%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

59kDa

Protein Length

526

NCBI Gene Symbol

IKZF2

Host or Source

Rabbit

Protein Name

Zinc finger protein Helios

Gene Name URL

IKZF2

Nucleotide Accession Number

NM_016260

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