PPHLN1 Antibody - N-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
Periphilin 1
Gene Aliases
CR, HSPC206, HSPC232
Gene ID
51535
Swiss Prot
Q8NEY8-2
Accession Number
NP_958923
Reactivity
Human, Mouse, Rat, Dog, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human PPHLN1
Target
The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
Partner Proteins
MTUS2; SNCAIP; CCDC57; TSGA10; UBC; BMI1; CLK2; CDK6; PAXIP1; BRCA1; APP; VIM; ELAVL1; NAGK; SEPT8; CDC37; SQSTM1; UFD1L; TP53BP2; BCL2L1; PPHLN1; PPL; CASP5; TOMM20; TGM2
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
MAYRRDEMWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDR
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Dog: 92%; Horse: 80%; Human: 100%; Mouse: 92%; Pig: 85%; Rabbit: 85%; Rat: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
43kDa
Protein Length
374
NCBI Gene Symbol
PPHLN1
Host or Source
Rabbit
Protein Name
Periphilin-1
Gene Name URL
PPHLN1
Nucleotide Accession Number
NM_201515
Curated Selection
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