TH1L Antibody - N-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

TH1-like (Drosophila)

Gene Aliases

TH1, TH1L, NELF-C, NELF-D, HSPC130

Gene ID

51497

Swiss Prot

Q8IXH7

Accession Number

NP_945327

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TH1L

Target

The NELF complex of proteins interacts with the DSIF protein complex to repress transcriptional elongation by RNA polymerase II. The protein encoded by this gene is an essential part of the NELF complex. Alternative translation initiation site usage results in the formation of two isoforms with different N-termini.

Partner Proteins

UBC; NELFA; PRMT5; ZNF638; UBE3A; POLR2C; SMAD4; ARAF; NELFB; NELFE; SUMO2; ATP1A1; CACNA1A; AR; FRMD5; ARPC4; HDAC11; ENDOV; SERF2; MTA1; AAMP; DNAJA1; TXK; GSTM4; EPRS; COPB2; RPS26; RPS14; RPS11; COX2; MCM7; EIF4G1; COX6C; COX6B1; COX5B; COX4I1; COX5A

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GEGEDDAEVQQECLHKFSTRDYIMEPSIFNTLKRYFQAGGSPENVIQLLS

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

66kDa

Protein Length

590

NCBI Gene Symbol

NELFCD

Host or Source

Rabbit

Protein Name

Negative elongation factor C/D

Gene Name URL

NELFCD

Nucleotide Accession Number

NM_198976

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