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PPP2R1A Antibody - N-terminal region (ARP57780_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Protein phosphatase 2, regulatory subunit A, beta

Gene Aliases

MRD36, PP2AA, PR65A, PP2AAALPHA, PP2A-Aalpha

Gene ID

5518

Swiss Prot

A8K7B7

Accession Number

NP_055040

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of HUMAN PPP2R1A

Target

PPP2R1A is a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. PPP2R1A is an alpha isoform of the constant regulatory subunit A.

Partner Proteins

CSDC2; UBC; PPP2R2A; PPP2R1B; PPP2CB; POLDIP2; MOB4; SRGAP2; ANKLE2; PSIP1; ESPL1; PPFIA3; PPFIA1; IRS4; CCDC6; TFAM; PPP1R12B; HSPA7; HSPA1A; FECH; CTNNA2; CLCN6; STRN; RPS19; RPS3; PPP2R5E; PPP2R5D; PPP2R5C; PPP2CA; PEX1; LOC730668; DGKH; RAVER1; CCDC43

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

IDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVL

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

64kDa

Protein Length

589

NCBI Gene Symbol

PPP2R1A

Host or Source

Rabbit

Protein Name

Protein phosphatase 2 (Formerly 2A), regulatory subunit A (PR 65), alpha isoform EMBL EAW72066.1

Gene Name URL

PPP2R1A

Nucleotide Accession Number

NM_014225

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