RAD51L1 Antibody - middle region

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Product Specifications

CAS Number

9007-83-4

Gene Name

RAD51 homolog B (S. cerevisiae)

Gene Aliases

REC2, R51H2, RAD51L1

Gene ID

5890

Swiss Prot

O15315-1

Accession Number

NP_598194

Reactivity

Human, Mouse, Cow

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RAD51L1

Target

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.

Partner Proteins

FAM9B; SWSAP1; UBC; HIST1H2BG; HIST2H4A; RAD51D; HIST1H3A; RAD51C; H1F0; XRCC2; RAD51; HIST1H1A; HIST3H2BB; HIST3H3; HIST4H4

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

IPVILTNQITTHLSGALASQADLVSPADDLSLSEGTSGSSCVIAALGNTW

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Human: 100%; Mouse: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

38kDa

Protein Length

350

NCBI Gene Symbol

RAD51B

Host or Source

Rabbit

Protein Name

DNA repair protein RAD51 homolog 2

Gene Name URL

RAD51B

Nucleotide Accession Number

NM_133510

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