MYL6 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Myosin, light chain 6, alkali, smooth muscle and non-muscle

Gene Aliases

LC17, ESMLC, LC17A, LC17B, MLC-3, MLC1SM, MLC3NM, MLC3SM, LC17-GI, LC17-NM

Gene ID

4637

Swiss Prot

P60660

Accession Number

NP_524147

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MYL6

Target

MYL6 contains 3 EF-hand domains. It is the regulatory light chain of myosin. MYL6 does not bind calcium. Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain that is expressed in smooth muscle and non-muscle tissues. Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene.

Partner Proteins

ADAMTS12; UBC; MDM2; SUZ12; MYL12A; MYH9; MYH14; GRIPAP1; UBD; GLP1R; PAN2; VCAM1; MLH1; ITGA4; FN1; TSGA10; ESR1; HSP90AB1; DES; ATP5B; MYL6B; LRRK2; CUL1; CDK2; ARRB1; ARRB2; SUMO2; SRRM2; USP45; USP46; USP18; MOB4; DNAJB9; NUDT21; EWSR1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

CDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKV

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 90%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

17kDa

Protein Length

151

NCBI Gene Symbol

MYL6

Host or Source

Rabbit

Protein Name

Myosin light polypeptide 6

Gene Name URL

MYL6

Nucleotide Accession Number

NM_079423

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