TRIB3 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Tribbles homolog 3 (Drosophila)

Gene Aliases

NIPK, SINK, TRB3, SKIP3, C20orf97

Gene ID

57761

Swiss Prot

Q96RU7

Accession Number

NP_066981

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TRIB3

Target

The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1.

Partner Proteins

RPGRIP1; UBC; DDIT3; ATF4; RFWD2; PRMT5; AKT1; APP; SMURF1; CDC25A; BMPR2; SMAD3; BCL6; COPS6; RBM48; EEF1G; SETDB1; GIT1; GDF9; KAT5; AKT2; RELA; ATF5; HRSP12; TIAF1; MCM3AP; LTBP4; SIAH1; RBM4; PSMA3; RPSA; HLA-B; GRN; FN1; CSNK2B

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

YVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHV

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 93%; Guinea Pig: 86%; Human: 100%; Rabbit: 86%; Rat: 79%; Sheep: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

39kDa

Protein Length

358

NCBI Gene Symbol

TRIB3

Host or Source

Rabbit

Protein Name

Tribbles homolog 3

Gene Name URL

TRIB3

Nucleotide Accession Number

NM_021158

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