Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

ALS2 Antibody - middle region

Click here to learn more about Aviva's By-Request Conjugation Service.//here

Product Specifications

CAS Number

9007-83-4

Gene Name

Amyotrophic lateral sclerosis 2 (juvenile)

Gene Aliases

ALSJ, PLSJ, IAHSP, ALS2CR6

Gene ID

57679

Swiss Prot

Q96Q42

Accession Number

NP_065970

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ALS2

Target

The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

VCP; UBC; YWHAB

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ALRGMSDLPPYGSGSSVQRQEPPISRSAKYTFYKDPRLKDATYDGRWLSG

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

184kDa

Protein Length

1657

NCBI Gene Symbol

ALS2

Host or Source

Rabbit

Protein Name

Alsin

Gene Name URL

ALS2

Nucleotide Accession Number

NM_020919

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Tia1 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
46685114 3x 1.0 µg

Tia1 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

Ask
View Details
Phospho-rat CCNB3 (S284) Antibody
MBS9204995-01 0.08 mL

Phospho-rat CCNB3 (S284) Antibody

Ask
View Details
Phospho-rat CCNB3 (S284) Antibody
MBS9204995-02 0.4 mL

Phospho-rat CCNB3 (S284) Antibody

Ask
View Details
Phospho-rat CCNB3 (S284) Antibody
MBS9204995-03 5x 0.4 mL

Phospho-rat CCNB3 (S284) Antibody

Ask
View Details
PHF3 (NM_001290259) Human Tagged ORF Clone
RG240224 10 µg

PHF3 (NM_001290259) Human Tagged ORF Clone

Ask
View Details
MLST8 Antibody, HRP conjugated
MBS7104674-01 0.05 mg

MLST8 Antibody, HRP conjugated

Ask
View Details