HMCES Antibody - N-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Chromosome 3 open reading frame 37

Gene Aliases

DC12, SRAPD1, C3orf37

Gene ID

56941

Swiss Prot

Q96FZ2

Accession Number

XP_005247693

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human HMCES

Target

HMCES specifically binds 5-hydroxymethylcytosine (5hmC) - containing DNA in stem cells, suggesting that it acts as a specific reader of 5hmC in stem cells (By similarity) . IT may act as a peptidase; experimental evidences are however required to confirm this prediction.

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GQQRLPEWRDPDKYCPSYNKSPQSNSPVLLSRLHFEKDADSSERIIAPMR

Applications

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 85%; Dog: 92%; Horse: 85%; Human: 100%; Mouse: 92%; Pig: 77%; Rabbit: 92%; Rat: 92%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

38kDa

Protein Length

354

NCBI Gene Symbol

HMCES

Host or Source

Rabbit

Protein Name

UPF0361 protein C3orf37

Gene Name URL

HMCES

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