CDCA7L Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Cell division cycle associated 7-like

Gene Aliases

R1, JPO2, RAM2

Gene ID

55536

Swiss Prot

B3KTR5

Accession Number

NP_001120842

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CDCA7L

Target

CDCA7L plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter.CDCA7L plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. CDCA7L is involved in apoptotic signaling pathways. CDCA7L may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.

Partner Proteins

KRTAP10-7; TRIM42; MORN3; BEND7; FAM9B; DEDD2; SSX2IP; ING5; TRAF3IP3; CEP70; CCDC33; CARD9; PRDM14; ZNF250; UTP3; CTNNBL1; ZNF821; CDCA7L; TFPT; ABT1; PRPF31; PPP1R16B; EIF4A3; STX11; UBL4A; TADA2A; NOP2; MFAP1; MDFI; LMO1; DAXX; BYSL; ANKRD11; SUV39H1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PPCRGICNCSYCRKRDGRCATGILIHLAKFYGYDNVKEYLESLQKELVED

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Yeast: 90%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

46kDa

Protein Length

420

NCBI Gene Symbol

CDCA7L

Host or Source

Rabbit

Protein Name

Cell division cycle-associated 7-like protein

Gene Name URL

CDCA7L

Nucleotide Accession Number

NM_001127370

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