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NLRP2 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

NLR family, pyrin domain containing 2

Gene Aliases

NBS1, PAN1, NALP2, PYPAF2, CLR19.9

Gene ID

55655

Swiss Prot

Q9NX02

Accession Number

NP_060322

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human NLRP2

Target

NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030) . They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]) .

Partner Proteins

SUGT1; APP; FAF1; PYCARD; IKBKG; IKBKB; CHUK; HSP90AA1; UBC; MRE11A; PYDC2; CARD8

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

FETLTCSSGTLRTLRLKIDDFNDELNKLLEEIEEKNPQLIIDTEKHHPWA

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

120kDa

Protein Length

1062

NCBI Gene Symbol

NLRP2

Host or Source

Rabbit

Protein Name

NACHT, LRR and PYD domains-containing protein 2

Gene Name URL

NLRP2

Nucleotide Accession Number

NM_017852

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