What is the catalog number for MRE11 Antibody - middle region?

The catalog number for MRE11 Antibody - middle region is ARP56645_P050-25UL.

What sizes are available for MRE11 Antibody - middle region?

MRE11 Antibody - middle region is available in the following size(s): 25 µL.

Is MRE11 Antibody - middle region in stock?

MRE11 Antibody - middle region is currently made to order / not held in immediate stock. Contact us for lead time.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

MRE11 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

MRE11 homolog, double strand break repair nuclease

Gene Aliases

ATLD, HNGS1, MRE11A, MRE11B

Gene ID

4361

Swiss Prot

P49959

Accession Number

NP_005582

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human MRE11A

Target

This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Partner Proteins

HUWE1; CIAO1; ATRX; BRCA1; RPA3; RPA2; RPA1; EED; ABCF1; C14orf166; RTCB; RPL26L1; NELFB; IGF2BP3; LRRFIP1; MAP7; EIF2B2; EIF2B3; YBX3; RPL27; RFC4; QARS; NMT1; HNRNPM; ILF2; HNRNPU; HNRNPA2B1; FLII; DHX9; DDX1; LMNA; PAN2; UBC; MCM2; GINS1; MDC1; RNF8; C

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RFRETRQKNTNEEDDEVREAMTRARALRSQSEESASAFSADDLMSIDLAE

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol