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RFC1 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Replication factor C (activator 1) 1, 145kDa

Gene Aliases

A1, RFC, PO-GA, RECC1, CANVAS, MHCBFB, RFC140

Gene ID

5981

Swiss Prot

P35251-2

Accession Number

NP_002904

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RFC1

Target

The protein encoded by this gene is the large subunit of replication factor C, which is a five subunit DNA polymerase accessory protein. Replication factor C is a DNA-dependent ATPase that is required for eukaryotic DNA replication and repair. The protein acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It also may have a role in telomere stability.

Partner Proteins

SPRTN; UBC; PCNA; RPA3; RPA2; RPA1; YWHAQ; SMC1A; RFC4; NOTCH1; WDR18; RBM14; RFC5; RFC3; RFC2; LAMP2; MYOC; SIRT7; SUMO2; HDGF; RAD17; CSNK2B; tat; SAP25; ZSCAN1; SSBP3; PMS1; CEBPA; BRCA1; RFC1; BRD4; HDAC1; CASP3; TCEAL1; CCND1; RELA; CDK4; CHTF18; SMA

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

AQAIYASVLPGELMRGYMTQFPTFPSWLGKHSSTGKHDRIVQDLALHMSL

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

128kDa

Protein Length

1147

NCBI Gene Symbol

RFC1

Host or Source

Rabbit

Protein Name

Replication factor C subunit 1

Gene Name URL

RFC1

Nucleotide Accession Number

NM_002913

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