RANGAP1 antibody - N-terminal region (ARP56509_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Ran GTPase activating protein 1

Gene Aliases

SD, Fug1, RANGAP

Gene ID

5905

Swiss Prot

P46060

Accession Number

NP_002874

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human RANGAP1

Target

RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGA

Partner Proteins

SENP2; SENP1; SUMO1; UBE2I; SUMO2; SUMO3; RANBP2; UBC; NEDD8; RNF2; rev; TP53RK; EFTUD1; NIF3L1; RPRD1B; OSGEP; PANK4; THG1L; NSUN2; UFM1; IPO11; SH3GLB1; TPRKB; EEF2K; DBNL; KIAA1279; ACTR2; ACTR3; ARPC1B; SAE1; TPD52L2; PPP2R5D; LPP; CALU; BAG1; ARPC2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDS

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

63kDa

Protein Length

587

NCBI Gene Symbol

RANGAP1

Host or Source

Rabbit

Protein Name

Ran GTPase-activating protein 1

Gene Name URL

RANGAP1

Nucleotide Accession Number

NM_002883

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