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PIM1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Pim-1 oncogene

Gene Aliases

PIM

Gene ID

5292

Swiss Prot

P11309-2

Accession Number

NP_002639

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PIM1

Target

PIM1 may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. Isoform 2 promotes the G1/S transition of the cell cycle via up-regulation of CDK2 activity and phosphorylation of CDKN1B, resulting in enhanced nuclear export and

Partner Proteins

FXR2; NHLH1; FH; BEND7; HEXIM2; BANP; TFPT; ZBTB1; UBC; APP; MARK3; HSP90AA1; HSPA4; PIM1; MDM2; ELAVL1; FZR1; SKP2; PPP2R5E; PPP2R4; PPP2CA; PIN1; CDC34; CDC20; ABCB1; HIST2H3C; MYC; MAX; SNX6; CBX1; CBX3; BAD; HIST3H3; SND1; PTPRO; NFATC1; SHMT1; EPHA3

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFG

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

45kDa

Protein Length

404

NCBI Gene Symbol

PIM1

Host or Source

Rabbit

Protein Name

Serine/threonine-protein kinase pim-1

Gene Name URL

PIM1

Nucleotide Accession Number

NM_002648

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