PDE4B Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Phosphodiesterase 4B, cAMP-specific

Gene Aliases

DPDE4, PDEIVB

Gene ID

5142

Swiss Prot

Q5TEK5

Accession Number

NP_001032416

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PDE4B

Target

The specific function of this protein remains unknown.This gene is a member of the type IV, cyclic AMP (cAMP) -specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Partner Proteins

MAGEA11; RCBTB2; APOA1; ALB; PAFAH1B1; UBC; DISC1; PRKACA

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

QDILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEED

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 83%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

64kDa

Protein Length

564

NCBI Gene Symbol

PDE4B

Host or Source

Rabbit

Protein Name

Phosphodiesterase 4B, cAMP-specific (Phosphodiesterase E4 dunce homolog, Drosophila) EMBL CAI21750.1

Gene Name URL

PDE4B

Nucleotide Accession Number

NM_001037339

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS1474327-01 0.02 mg (E-Coli)

Recombinant Propionibacterium acnes Orotate phosphoribosyltransferase (pyrE)

Ask

View Details

MBS1474327-02 0.1 mg (E-Coli)

Recombinant Propionibacterium acnes Orotate phosphoribosyltransferase (pyrE)

Ask

View Details

MBS1474327-03 0.02 mg (Yeast)

Recombinant Propionibacterium acnes Orotate phosphoribosyltransferase (pyrE)

Ask

View Details

MBS1474327-04 0.1 mg (Yeast)

Recombinant Propionibacterium acnes Orotate phosphoribosyltransferase (pyrE)

Ask

View Details

MBS1474327-05 0.02 mg (Baculovirus)

Recombinant Propionibacterium acnes Orotate phosphoribosyltransferase (pyrE)

Ask

View Details

MBS1474327-06 0.02 mg (Mammalian-Cell)

Recombinant Propionibacterium acnes Orotate phosphoribosyltransferase (pyrE)

Ask

View Details