GOPC Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Golgi-associated PDZ and coiled-coil motif containing

Gene Aliases

CAL, FIG, PIST, GOPC1, dJ94G16.2

Gene ID

57120

Swiss Prot

Q9HD26

Accession Number

NP_001017408

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human GOPC

Target

GOPC plays a role in intracellular protein trafficking and degradation. GOPC may regulate CFTR chloride currents and acid-induced ACCN3 currents by modulating cell surface expression of both channels. GOPC may also regulate the intracellular trafficking of the ADR1B receptor. GOPC may play a role in autophagy. Overexpression of GOPC results in CFTR intracellular retention and degradation in the lysosomes.PIST is a PDZ domain-containing Golgi protein. PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner.[supplied by OMIM].

Partner Proteins

BATF; SSNA1; VTN; MYLK; HCK; FOSL2; DPYD; RPL13AP17; C17orf67; ZSCAN1; LCLAT1; FAM9B; ZBTB49; ZNF564; SPATA8; RNF183; MORN4; MYOCD; MUM1; ZNF587; SLC25A18; CCDC102B; AKIRIN1; MRPL1; SEMA4G; RNF220; FAM90A1; PID1; ZNF581; CERCAM; RHOQ; PARK7; STARD3; HSF1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RNDLKRPMQAPPGHDQDSLKKSQGVGPIRKVLLLKEDHEGLGISITGGKE

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

50kDa

Protein Length

454

NCBI Gene Symbol

GOPC

Host or Source

Rabbit

Protein Name

Golgi-associated PDZ and coiled-coil motif-containing protein

Gene Name URL

GOPC

Nucleotide Accession Number

NM_001017408

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