L-163255 (free base)

L-163255 free base is an orally active spiropiperidine GH secretagogue. L-163255 (free base) can also increase plasma IGF-I level[1].

Product Specifications

CAS Number

[159634-54-5]

UNSPSC

12352005

Target

GHSR

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/l-163255-free-base.html

Smiles

CS(=O)(N1CC2(CCN(CC2)C([C@H](NC(C(C)(N)C)=O)CCCC3=CC=CC=C3)=O)C4=CC=CC=C41)=O

Molecular Formula

C28H38N4O4S

Molecular Weight

526.69

References & Citations

[1]C H Chang, et al. Growth hormone (GH) and insulin-like growth factor I responses after treatments with an orally active GH secretagogue L-163,255 in swine. Endocrinology. 1996 Nov;137 (11) :4851-6.|[2]Anargyros N Moulas, et al. Effect of the GH secretagogue L-163,255 and restricted feeding time on GH pulsatility in the rat. Eur J Endocrinol. 2002 Jul;147 (1) :143-8.