PYDC1 Antibody - N-terminal region (ARP55560_P050)
Product Specifications
CAS Number
9007-83-4
Gene Name
PYD (pyrin domain) containing 1
Gene Aliases
ASC2, POP1, PYC1, cPOP1
Gene ID
260434
Swiss Prot
Q8WXC3
Accession Number
NP_690865
Reactivity
Human, Cow, Dog, Goat, Guinea Pig, Horse, Yeast
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human PYDC1
Target
PYDC1 associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro- caspase-1 activation. It suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.
Partner Proteins
WDR82
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
REAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTD
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 83%; Dog: 83%; Goat: 83%; Guinea Pig: 85%; Horse: 83%; Human: 100%; Yeast: 77%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
9kDa
Protein Length
89
NCBI Gene Symbol
PYDC1
Host or Source
Rabbit
Protein Name
Pyrin domain-containing protein 1
Gene Name URL
PYDC1
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