NKIRAS1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

NFKB inhibitor interacting Ras-like 1

Gene Aliases

KBRAS1, kappaB-Ras1

Gene ID

28512

Swiss Prot

Q9NYS0

Accession Number

NP_065078

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NKIRAS1

Target

NKIRAS1 is an atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. NKIRAS1 may act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.

Partner Proteins

XRCC2; UBC; APP; NFKBIB; SMURF2; BMPR1B; TGFBR1; NFKBIA; ACVR1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

CETMEDVYMASVETDRGVKEQLHLYDTRGLQEGVELPKHYFSFADGFVLV

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

22kDa

Protein Length

192

NCBI Gene Symbol

NKIRAS1

Host or Source

Rabbit

Protein Name

NF-kappa-B inhibitor-interacting Ras-like protein 1

Gene Name URL

NKIRAS1

Nucleotide Accession Number

NM_020345

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

GTR15324566 1 Vial

Lentiviral human CCDC86 shRNA (UAS) - Lentiviral human CCDC86 shRNA (UAS, RFP) (25)

Ask

View Details

MR214592L4V 200 µL

Vmn2r9 (NM_001104621) Mouse Tagged ORF Clone Lentiviral Particle

Ask

View Details

MBS6187633-01 0.1 mL

ZFP161 (Zinc Finger Protein 161 Homolog (mouse), MGC126126, ZBTB14, ZF5, ZNF478) (PE)

Ask

View Details

MBS6187633-02 5x 0.1 mL

ZFP161 (Zinc Finger Protein 161 Homolog (mouse), MGC126126, ZBTB14, ZF5, ZNF478) (PE)

Ask

View Details

545762 200 µL

Cathelicidin Antimicrobial Peptide

Ask

View Details

abx377789-01 50 µg

C-C Motif Chemokine 3-Like 1 (CCL3L1) Antibody

Ask

View Details