SENP3 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

SUMO1/sentrin/SMT3 specific peptidase 3

Gene Aliases

SSP3, Ulp1, SMT3IP1

Gene ID

26168

Swiss Prot

Q9H4L4

Accession Number

NP_056485

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SENP3

Target

SENP3 is a protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. SENP3 deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability.

Partner Proteins

HIF1A; EP300; UBC; SUMO2; WDR5; ASH2L; KMT2D; RBBP5; KMT2A; MEN1; RNF2; HECW2; SOX2; LAS1L; PELP1; CDK6; CDK4; MOV10; CHCHD4; DHX15; ILF3; TRIM63; TRIM54; USP21; USP15; CDKN2A; RPS18; RPS11; RPS8; RPS4X; RPLP0; NPM1; PIDD1; NR1H2; TP53; MDM2; STUB1; HSP90

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PPPKPRLKSGGGFGPDPGSGTTVPARRLPVPRPSFDASASEEEEEEEEEE

Applications

IF, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

65kDa

Protein Length

574

NCBI Gene Symbol

SENP3

Host or Source

Rabbit

Protein Name

Sentrin-specific protease 3

Gene Name URL

SENP3

Nucleotide Accession Number

NM_015670

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