PPP6R1 Antibody - N-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Protein phosphatase 6, regulatory subunit 1

Gene Aliases

PP6R1, SAPS1, SAP190, KIAA1115

Gene ID

22870

Swiss Prot

Q9UPN7

Accession Number

NP_055746

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PPP6R1

Target

Protein phosphatase regulatory subunits, such as SAPS1, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS1 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 300141) (Stefansson and Brautigan, 2006 [PubMed 16769727]) .

Partner Proteins

UBC; AGO1; ANKRD52; MOB1B; ANKRD44; ACAD11; SRPRB; PPP6R3; MOB1A; CNOT10; ANKRD28; CNOT1; ILVBL; PFDN6; C2CD5; KNTC1; PPP6R2; GTF3C4; ARHGEF2; USP10; SGPL1; IKBKAP; TTF2; SRPR; PPP6C; PFDN5; PFDN2; PDCD2; HSPA4; HADHB; HADHA; ACSL3; ALDH3A2; EGFR; HDAC11

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MFWKFDLHTSSHLDTLLEREDLSLPELLDEEDVLQECKVVNRKLLDFLLQ

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

97kDa

Protein Length

881

NCBI Gene Symbol

PPP6R1

Host or Source

Rabbit

Protein Name

Serine/threonine-protein phosphatase 6 regulatory subunit 1

Gene Name URL

PPP6R1

Nucleotide Accession Number

NM_014931

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