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RABGEF1 Antibody - N-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

RAB guanine nucleotide exchange factor (GEF) 1

Gene Aliases

RAP1, RABEX5, rabex-5

Gene ID

27342

Swiss Prot

A8K3R3

Accession Number

NP_055319

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human RABGEF1

Target

RABGEF1 forms a complex with rabaptin-5 (RABPT5; MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A; MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]) .

Partner Proteins

TRIM15; CIPC; ZC2HC1C; TRIM54; RABGEF1; BLOC1S6; TXN2; THOC1; DAZAP2; UBC; TEAD4; RABEP1; DGCR6; TNKS1BP1; ROCK2; SLMAP; MON1A; RNF11; MON1B; RAB21; UBE2D3; UBE2D1; RAB5A; L1CAM; EEA1; ESR1; EGFR; RAB22A; GGA1; MAPK1; HRAS; YWHAG; YWHAB; KXD1; GGA2; RNF16

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MSLKSERRGIHVDQSDLLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQ

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

57kDa

Protein Length

491

NCBI Gene Symbol

RABGEF1

Host or Source

Rabbit

Protein Name

Rab5 GDP/GTP exchange factor

Gene Name URL

RABGEF1

Nucleotide Accession Number

NM_014504

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