EDC4 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Enhancer of mRNA decapping 4

Gene Aliases

GE1, Ge-1, RCD8, HEDL5, HEDLS, RCD-8

Gene ID

23644

Swiss Prot

Q6P2E9

Accession Number

NP_055144

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human EDC4

Target

In the process of mRNA degradation, EDC4 seems to play a role in mRNA decapping. It is the component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. EDC4 promotes complex formation between DCP1A and DCP2.It enhances the catalytic activity of DCP2 (in vitro) .

Partner Proteins

MDM2; DCP1B; DCP1A; UBC; DCP2; LGR4; WWOX; RPA3; RPA2; RPA1; BMI1; DIMT1; NELFB; IGF2BP3; G3BP1; EIF2B2; EIF2B3; RFC4; NMT1; ILF2; FKBP3; DDX1; ABCF1; ZFP36; YTHDC1; EDC3; vpu; GIT2; FBLN1; CCL5; UPF1; CRK; SIRT7; EIF2AK2; Edc4; Pds5a; tat

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LQEKQVICLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPV

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

152kDa

Protein Length

1401

NCBI Gene Symbol

EDC4

Host or Source

Rabbit

Protein Name

Enhancer of mRNA-decapping protein 4

Gene Name URL

EDC4

Nucleotide Accession Number

NM_014329

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