SFN Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Stratifin

Gene Aliases

YWHAS

Gene ID

2810

Swiss Prot

P31947

Accession Number

NP_006133

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SFN

Target

SFN is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. SFN binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, SFN regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.

Partner Proteins

FAM9B; RAB3IP; LONRF1; CCDC102B; ZC2HC1C; DTL; FAM53C; MKRN3; FOXO4; MAGEA1; CCNH; SIK3; ZFYVE19; YWHAZ; VCL; UBE2V1; SNRPF; UBE2R2; PAK2; G6PD; TARDBP; EGFR; BAD; MARK3; HDAC7; HDAC5; HDAC4; RAF1; CDC25C; MST1R; ABL1; HNRNPD; ATF2; TRIM32; COPS6; UBC; TP

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

VVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVL

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 86%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Sheep: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

28kDa

Protein Length

248

NCBI Gene Symbol

SFN

Host or Source

Rabbit

Protein Name

14-3-3 protein sigma

Gene Name URL

SFN

Nucleotide Accession Number

NM_006142

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