LGALS3BP Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Galectin 3 binding protein

Gene Aliases

90K, M2BP, gp90, CyCAP, BTBD17B, MAC-2-BP, TANGO10B

Gene ID

3959

Swiss Prot

Q08380

Accession Number

NP_005558

Reactivity

Human, Mouse, Rat, Cow, Dog

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human LGALS3BP

Target

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV) . It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.

Partner Proteins

GIGYF2; PRRC2C; CCT5; TUBB; CRTC2; RAVER1; TUBA1C; ENAH; CEP55; XRN2; CEP250; MAGED2; CCT8; CCT2; CCT4; CCT7; TUBGCP3; TUBB4B; TRAP1; BAG2; RPL23; IRS4; TUBA1A; MOGS; CCT3; TCP1; RPS4X; RPL38; HSPD1; HSP90AB1; HSP90AA1; HSPA8; HSPA5; HSPA1A; HNRNPU; CCT6A

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

NLSLYWSHEALFQKKTLQALEFHTVPFQLLARYKGLNLTEDTYKPRIYTS

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 83%; Dog: 83%; Human: 100%; Mouse: 100%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

63kDa

Protein Length

585

NCBI Gene Symbol

LGALS3BP

Host or Source

Rabbit

Protein Name

Galectin-3-binding protein

Gene Name URL

LGALS3BP

Nucleotide Accession Number

NM_005567

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