GBP2 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Guanylate binding protein 2, interferon-inducible

Gene ID

2634

Swiss Prot

P32456

Accession Number

NP_004111

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human GBP2

Target

GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) . GBP2 is a GTPase that converts GTP to GDP and GMP. Interferons are cytokines that have antiviral effects and inhibit tumor cell proliferation. They induce a large number of genes in their target cells, including those coding for the guanylate-binding proteins (GBPs) . GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) . The protein encoded by this gene is a GTPase that converts GTP to GDP and GMP.

Partner Proteins

CNDP2; NANS; RPS6KA1; PEPD; MVD; GSR; GNS; GLA; G6PD; CASP7; CAPN1; ASS1; GSK3B; GADD45A; CSNK2B; BNIP3L; BID; ANXA7; MAPK8IP2; STK3; KLHL20; BTBD2; LSM2; PAFAH1B3; PPP1R8; MAGI1; TFG; SERPINB9; SEPHS1; FXR1; HSPE1; SAT1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

HTKGIWMWCVPHPKKPEHTLVLLDTEGLGDIEKGDNENDSWIFALAILLS

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 79%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

67kDa

Protein Length

591

NCBI Gene Symbol

GBP2

Host or Source

Rabbit

Protein Name

Interferon-induced guanylate-binding protein 2

Gene Name URL

GBP2

Nucleotide Accession Number

NM_004120

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