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FKBP5 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

FK506 binding protein 5

Gene Aliases

P54, AIG6, FKBP51, FKBP54, PPIase, Ptg-10

Gene ID

2289

Swiss Prot

Q13451

Accession Number

NP_004108

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human FKBP5

Target

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites.

Partner Proteins

LRRC40; CXorf57; EGLN1; AGO2; CACYBP; CHORDC1; AGO1; KIAA1279; NUDCD3; GLMN; CDC37; SUGT1; PTGES3; NUDC; AHSA1; DNAJB6; AURKB; IKBKG; IRS4; TUBA1A; TTC4; PYGL; PDCD2; CDK11A; HGH1; C14orf80; MCMBP; PNPLA2; ANKMY2; CDC37L1; MCM4; ILK; HSP90AB1; HSP90AA1; H

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

KMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESW

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

51kDa

Protein Length

457

NCBI Gene Symbol

FKBP5

Host or Source

Rabbit

Protein Name

Peptidyl-prolyl cis-trans isomerase FKBP5

Gene Name URL

FKBP5

Nucleotide Accession Number

NM_004117

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