What is the catalog number for GRN Antibody - middle region (ARP54642_P050)?

The catalog number for GRN Antibody - middle region (ARP54642_P050) is ARP54642_P050.

What sizes are available for GRN Antibody - middle region (ARP54642_P050)?

GRN Antibody - middle region (ARP54642_P050) is available in the following size(s): 100 µL.

Is GRN Antibody - middle region (ARP54642_P050) in stock?

GRN Antibody - middle region (ARP54642_P050) is currently made to order / not held in immediate stock. Contact us for lead time.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

GRN Antibody - middle region (ARP54642_P050)

Selected Variant

ARP54642_P050

Size: 100 µL

Product Specifications

CAS Number

9007-83-4

Gene Name

Granulin

Gene Aliases

GEP, GP88, PEPI, PGRN, CLN11, PCDGF

Gene ID

2896

Swiss Prot

P28799-2

Reactivity

Human, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human GRN

Target

Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.

Partner Proteins

OTX1; HOXA1; DLX2; SGTA; KRTAP26-1; KRTAP10-7; CCDC33; ARFGAP1; FANCL; NLK; GLRX3; EED; HECW2; Hk3; RPS6KA1; NPM1; POT1; FRAT1; YY1; TGM2; RAC1; PRKAB2; PIK3R2; SMAD9; KRT18; CRY1; CFTR; CCNG1; FBXO6; GFI1B; ATN1; CDK2; CRKL; VHL; SIRT3; ATXN7; CACNA1A; C

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

QAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQAL

Applications

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Horse: 86%; Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

64 kDa

Protein Length

593

NCBI Gene Symbol

GRN

Host or Source

Rabbit

Protein Name

Granulins

Gene Name URL

GRN

Price

Frequently Asked Questions

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