What is the catalog number for GRN Antibody - middle region (ARP54641_P050)?

The catalog number for GRN Antibody - middle region (ARP54641_P050) is ARP54641_P050.

What sizes are available for GRN Antibody - middle region (ARP54641_P050)?

GRN Antibody - middle region (ARP54641_P050) is available in the following size(s): 100 µL.

Is GRN Antibody - middle region (ARP54641_P050) in stock?

GRN Antibody - middle region (ARP54641_P050) is currently made to order / not held in immediate stock. Contact us for lead time.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

GRN Antibody - middle region (ARP54641_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Granulin

Gene Aliases

GEP, GP88, PEPI, PGRN, CLN11, PCDGF

Gene ID

2896

Swiss Prot

P28799-2

Accession Number

NP_002078

Reactivity

Human, Cow, Dog, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human GRN

Target

Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.

Partner Proteins

OTX1; HOXA1; DLX2; SGTA; KRTAP26-1; KRTAP10-7; CCDC33; ARFGAP1; FANCL; NLK; GLRX3; EED; HECW2; Hk3; RPS6KA1; NPM1; POT1; FRAT1; YY1; TGM2; RAC1; PRKAB2; PIK3R2; SMAD9; KRT18; CRY1; CFTR; CCNG1; FBXO6; GFI1B; ATN1; CDK2; CRKL; VHL; SIRT3; ATXN7; CACNA1A; C

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

CPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGD

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 92%; Horse: 92%; Human: 100%; Rabbit: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

47 kDa

Protein Length

438

NCBI Gene Symbol

GRN

Host or Source

Rabbit

Protein Name

Granulins

Gene Name URL

GRN

Nucleotide Accession Number

NM_002087

Frequently Asked Questions

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