What is the catalog number for UBE4B Antibody - N-terminal region?

The catalog number for UBE4B Antibody - N-terminal region is ARP54552_P050-25UL.

What sizes are available for UBE4B Antibody - N-terminal region?

UBE4B Antibody - N-terminal region is available in the following size(s): 25 µL.

Is UBE4B Antibody - N-terminal region in stock?

UBE4B Antibody - N-terminal region is currently made to order / not held in immediate stock. Contact us for lead time.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

UBE4B Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Ubiquitination factor E4B

Gene Aliases

E4, UFD2, HDNB1, UBOX3, UFD2A

Gene ID

10277

Swiss Prot

O95155

Accession Number

NP_001099032

Reactivity

Human, Dog, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human UBE4B

Target

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B is an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. The gene that encodes the protein is also the strongest candidate in the neuroblastoma tumor suppressor genes. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Partner Proteins

TRIP12; UBC; FBXW11; HGS; STAM; TP53; MDM2; NUSAP1; NUDCD3; RBM12; PDE3A; CDKN2A; UBL7; UBE2D3; CDC27; TTK; IGBP1; HDLBP; TTC9C; MRPL53; ZFYVE19; SARNP; SRPRB; VPS35; UBA6; VPS29; UFM1; SBDS; VPS36; UBQLN1; UBXN7; UBE2C; AHCYL1; SSSCA1; SF3B4; PPIF; SCO2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQL

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol