What is the catalog number for LCK Antibody - N-terminal region?

The catalog number for LCK Antibody - N-terminal region is ARP54524_P050-25UL.

What sizes are available for LCK Antibody - N-terminal region?

LCK Antibody - N-terminal region is available in the following size(s): 25 µL.

Is LCK Antibody - N-terminal region in stock?

LCK Antibody - N-terminal region is currently made to order / not held in immediate stock. Contact us for lead time.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

LCK Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Lymphocyte-specific protein tyrosine kinase

Gene Aliases

LSK, YT16, IMD22, p56lck, pp58lck

Gene ID

3932

Swiss Prot

P06239-2

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human LCK

Target

LCK is a member of the Src family of protein tyrosine kinases (PTKs) . It is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. LCK localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules.

Partner Proteins

LZTS2; CDKAL1; BAG6; UBC; WASL; WAS; env; SMAD3; SMAD2; MAPK1; HSP90AA1; Mbp; HAVCR2; PTPN22; G3BP1; nef; LAT; KHDRBS1; ADAM15; ZAP70; PAK2; LCK; CBL; SOCS3; SOCS2; SOCS1; IL2RB; CISH; YWHAQ; AJUBA; CD5; CBLB; SKAP1; SYK; SOS1; CD38; CD247; CD3E; FAM174A

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ENCHYPIVPLDGKGTLLIRNGSEVRDPLVTYEGSNPPASPLQDNLVIALH

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol