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ALAS1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Aminolevulinate, delta-, synthase 1

Gene Aliases

ALAS, MIG4, ALAS3, ALASH, ALAS-H

Gene ID

211

Swiss Prot

P13196

Accession Number

NP_000679

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ALAS1

Target

Delta-aminolevulinate synthase (ALAS; EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2.

Partner Proteins

FAM127C; KLHL35; ZNF564; TEKT4; DUSP19; SNX20; MTFR2; LONRF1; ZMAT1; CDC73; TTC23; CERK; SH2D4A; EP400; C2orf42; GNL3L; CCHCR1; POLDIP2; ZFYVE26; USP20; TMSB10; ZNF175; WIPF1; UBC; TMSB4XP6; TMSB4XP2; TMSB4XP1; TMSB4X; TCEA2; PPL; BCL7A; ALAS1; PLAU; VHL

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ETSAGPSVVSVKTDGGDPSGLLKNFQDIMQKQRPERVSHLLQDNLPKSVS

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Sheep: 93%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

71 kDa

Protein Length

640

NCBI Gene Symbol

ALAS1

Host or Source

Rabbit

Protein Name

5-aminolevulinate synthase, nonspecific, mitochondrial

Gene Name URL

ALAS1

Nucleotide Accession Number

NM_000688

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