ATG16L1 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

ATG16 autophagy related 16-like 1 (S. cerevisiae)

Gene Aliases

IBD10, WDR30, APG16L, ATG16A, ATG16L

Gene ID

55054

Swiss Prot

Q676U5

Accession Number

NP_110430

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ATG16L1

Target

Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy.Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy (Mizushima et al., 2003 [PubMed 12665549]) .[supplied by OMIM].

Partner Proteins

WIPI2; RB1CC1; DEDD2; TRAF3IP3; NOD2; TMEM59; TLR2; SUMO2; ATG13; ATG5; ULK1; UBC; TNK2; SYNPO2; ATG12; NOD1; WDFY3; APP; RAB33B; RAB35; RAB3D; RAB33A; HSPA4; FCGRT; CLTC; AP2M1; ELAVL1; MAP1LC3C; MAP1LC3B; ATG3; CCT2; CCT7; AGPS; GAN; CCT3; SNAPC4; ATG16

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

TSPVRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNVDTHPG

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

68kDa

Protein Length

607

NCBI Gene Symbol

ATG16L1

Host or Source

Rabbit

Protein Name

Autophagy-related protein 16-1

Gene Name URL

ATG16L1

Nucleotide Accession Number

NM_030803

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