ATG16L1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

ATG16 autophagy related 16-like 1 (S. cerevisiae)

Gene Aliases

IBD10, WDR30, APG16L, ATG16A, ATG16L

Gene ID

55054

Swiss Prot

Q676U5

Accession Number

NP_060444

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ATG16L1

Target

Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy.Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy (Mizushima et al., 2003 [PubMed 12665549]) .[supplied by OMIM].

Partner Proteins

WIPI2; RB1CC1; DEDD2; TRAF3IP3; NOD2; TMEM59; TLR2; SUMO2; ATG13; ATG5; ULK1; UBC; TNK2; SYNPO2; ATG12; NOD1; WDFY3; APP; RAB33B; RAB35; RAB3D; RAB33A; HSPA4; FCGRT; CLTC; AP2M1; ELAVL1; MAP1LC3C; MAP1LC3B; ATG3; CCT2; CCT7; AGPS; GAN; CCT3; SNAPC4; ATG16

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

QYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQ

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol