FBXO31 antibody - middle region (ARP53775_P050)
Product Specifications
CAS Number
9007-83-4
Gene Name
F-box protein 31
Gene Aliases
FBX14, Fbx31, MRT45, FBXO14, pp2386
Gene ID
79791
Swiss Prot
Q5XUX0
Accession Number
NP_079011
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human FBXO31
Target
FBXO31 is the component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. FBXO31 specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. FBXO31 may act as a tumor suppressor.
Partner Proteins
CDT1; UBE2L6; UBE2D1; CCND1; CUL1; MAP2K6; PARD6A; SKP1; COPS5; RBX1
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
QGPRESQPSPAQPRAEAPSKGPDGTPGEDGGEPGDAVAAAEQPAQCGQGQ
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
40kDa
Protein Length
367
NCBI Gene Symbol
FBXO31
Host or Source
Rabbit
Protein Name
F-box only protein 31
Gene Name URL
FBXO31
Nucleotide Accession Number
NM_024735
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