What is the catalog number for SOCS7 Antibody - N-terminal region (ARP53701_P050)?

The catalog number for SOCS7 Antibody - N-terminal region (ARP53701_P050) is ARP53701_P050.

What sizes are available for SOCS7 Antibody - N-terminal region (ARP53701_P050)?

SOCS7 Antibody - N-terminal region (ARP53701_P050) is available in the following size(s): 100 µL.

Is SOCS7 Antibody - N-terminal region (ARP53701_P050) in stock?

SOCS7 Antibody - N-terminal region (ARP53701_P050) is currently made to order / not held in immediate stock. Contact us for lead time.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

SOCS7 Antibody - N-terminal region (ARP53701_P050)

Selected Variant

ARP53701_P050

Size: 100 µL

Product Specifications

CAS Number

9007-83-4

Gene Name

Suppressor of cytokine signaling 7

Gene Aliases

NAP4, NCKAP4

Gene ID

30837

Swiss Prot

O14512-2

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human SOCS7

Target

SOCS7 regulates signaling cascades probably through protein ubiquitination and/or sequestration. It functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. It inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. SOCS7 may be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Partner Proteins

SEPT6; SORBS3; STAT5A; STAT3; CUL5; IRS4; PIK3R2; TUBB4B; TUBA1A; IRS2; NCK1; PLCG1; PIK3R1; EGFR; GRB2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTS

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 92%; Guinea Pig: 83%; Horse: 100%; Human: 100%; Mouse: 85%; Pig: 92%; Rabbit: 100%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

36kDa

Protein Length

331

NCBI Gene Symbol

SOCS7

Host or Source

Rabbit

Protein Name