AURKA Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Aurora kinase C

Gene Aliases

AIK, ARK1, AURA, BTAK, STK6, STK7, STK15, PPP1R47

Gene ID

6790

Swiss Prot

O14965

Accession Number

NP_940839

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human AURKA

Target

AURKA is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. It is found at the centrosome in interphase cells and at the spindle poles in mitosis. This protein may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.

Partner Proteins

CHFR; GADD45A; RPLP2; RPLP0; RPL38; RPL30; RPL27; RPL22; RPL12; RPL11; PSMB7; PSMB5; PSMA6; PSMA5; PSMA1; MAPK6; PPP6C; PCMT1; YBX1; NPM1; NCL; MFAP4; LYZ; ILF3; ILF2; IARS; HSPD1; HSP90AB1; HSP90AA1; HSPA9; HSPA8; HSPA5; HSPA2; HSPA1A; HNRNPU; HNRNPA2B1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

REKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYF

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Sheep: 77%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

44kDa

Protein Length

403

NCBI Gene Symbol

AURKA

Host or Source

Rabbit

Protein Name

Aurora kinase A

Gene Name URL

AURKA

Nucleotide Accession Number

NM_198437

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