KHDRBS2 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

KH domain containing, RNA binding, signal transduction associated 2

Gene Aliases

SLM1, SLM-1

Gene ID

202559

Swiss Prot

Q5VWX1

Accession Number

NP_689901

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human KHDRBS2

Target

KHDRBS2 is a RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. KHDRBS2 induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. KHDRBS2 may function as an adapter protein for Src kinases during mitosis. KHDRBS2 binds both poly (A) and poly (U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability.

Partner Proteins

HBZ; DOCK2; CIRBP; TYMSOS; LINC01018; KHDRBS2; ZFC3H1; CATSPER1; YTHDC1; PRR3; NABP1; AEN; NCOA5; NPDC1; RBMX; PRPF31; CHTOP; HNRNPR; MTA1; TYK2; SULT1A3; SPG7; SDCBP; RBM3; PTK6; UBC; KHDRBS3; HNRNPK; LYN; HNRNPC; HNRNPA2B1; HNRNPA1; FGG; FGB; FGA; DSG1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EEIEKFQGSDGKKEDEEKKYLDVISNKNIKLSERVLIPVKQYPKFNFVGK

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

39kDa

Protein Length

349

NCBI Gene Symbol

KHDRBS2

Host or Source

Rabbit

Protein Name

KH domain-containing, RNA-binding, signal transduction-associated protein 2

Gene Name URL

KHDRBS2

Nucleotide Accession Number

NM_152688

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