MED8 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Mediator complex subunit 8

Gene Aliases

ARC32

Gene ID

112950

Swiss Prot

Q96G25-2

Accession Number

NP_443109

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MED8

Target

MED8 is a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. MED8 also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase.This gene encodes a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. The product of this gene also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase. Two alternative transcripts encoding different isoforms have been described.

Partner Proteins

PNMA1; KRT40; CDK19; CDK8; MED19; MED26; FBXW7; EPAS1; MED29; MED18; CPSF1; MED4; MED16; MED12; MED24; MED21; MED14; MED1; HIST1H1E; APP; MED11; SUMO2; MED10; RBX1; CTDP1; CUL2; TCEB2; TCEB1; MED28; OBFC1; ZC3H13; TRIP4; TADA2A; THOC7; PHYHIP; MED20; MED9

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MQREEKQLEASLDALLSQVADLKNSLGSFICKLENEYGRLTWPSVLDSFA

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol