DNM1L Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Dynamin 1-like

Gene Aliases

DLP1, DRP1, DVLP, EMPF, OPA5, EMPF1, DYMPLE, HDYNIV

Gene ID

10059

Swiss Prot

O00429

Accession Number

NP_036192

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DNM1L

Target

The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.

Partner Proteins

ZBTB24; UBC; SCG3; SH3GL1; RRM2; MAGEA3; MAGEA1; MARCH5; EGFR; VPS26A; SSB; CARS; ATP6V1C1; APEH; PSMG3; FAM129B; TBC1D15; CYHR1; ARFIP1; JMJD6; SEC24A; SOX2; DNM1L; MIEF2; MFF; PEX14; LRRK2; MIEF1; COPS5; GABRR1; MUL1; SUMO2; PARK2; PEX25; PEX11G; PEX11A

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

IRQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVG

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 85%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

82 kDa

Protein Length

736

NCBI Gene Symbol

DNM1L

Host or Source

Rabbit

Protein Name

Dynamin-1-like protein

Gene Name URL

DNM1L

Nucleotide Accession Number

NM_012062

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