PNKP antibody - N-terminal region (ARP52311_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Polynucleotide kinase 3'-phosphatase

Gene Aliases

PNK, AOA4, MCSZ, CMT2B2, EIEE10

Gene ID

11284

Swiss Prot

Q96T60

Accession Number

NP_009185

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PNKP

Target

This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.

Partner Proteins

ZNF639; IKZF1; TNIP1; ZBTB14; RPA3; RPA2; RPA1; EED; rev; KDM1A; SUV39H1; HNRNPU; GZMK; XRCC6; CDK11B; PARP1; MCM3; SMAD5; LIG4; XRCC1; TCOF1; SSRP1; PRKDC; NRD1; NASP; MCM5; C18orf25; UBE2O; GEMIN4; AGTPBP1; PNKP; SUPT16H; VPRBP; NOLC1; TRIM26; XRCC5; XR

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MGEVEAPGRLWLESPPGGAPPIFLPSDGQALVLGRGPLTQVTDRKCSRTQ

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol