HAX1 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

HCLS1 associated protein X-1

Gene Aliases

SCN3, HS1BP1, HCLSBP1

Gene ID

10456

Swiss Prot

O00165

Accession Number

NP_001018238

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HAX1

Target

HAX1 is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease.

Partner Proteins

ERLIN2; UBC; BIRC3; CEP250; TUBGCP2; TUBGCP3; MAPK10; HIPK1; DYRK4; ZNF420; POLR1D; ZNRD1; RBX1; STAT5B; RPA1; PPP3CC; CFTR; EWSR1; SHC1; HTRA2; NEDD4L; CUL3; CUL4A; PIDD1; SVIL; EBNA-LP; AMFR; HNF4G; AKAP10; TUBB4A; ABCC4; MATN4; EIF3D; RGS1; HSP90AB1; H

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

QPAPDWGSQRPFHRFDDVWPMDPHPRTREDNDLDSQVSQEGLGPVLQPQP

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol