SAE1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

SUMO1 activating enzyme subunit 1

Gene Aliases

AOS1, SUA1, UBLE1A, HSPC140

Gene ID

10055

Swiss Prot

Q9UBE0

Accession Number

NP_005491

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SAE1

Target

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]) .

Partner Proteins

FUS; USP39; SUMO2; HSPA2; HSPA1A; UBC; TRMT10A; DPP9; RPRD1B; NPLOC4; OSGEP; PANK4; WDR4; CUL5; TPD52L2; SRP14; RANGAP1; PPP2R5E; MCM3; LPP; DHPS; CALU; ADSL; AARS; PDE12; TP53RK; UBE2I; UBA2; BAG3; PTK2; IL3RA; APP; SUMO1; ETV4; BCL6; UBE2E3; SUMO3; SP10

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

VTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol