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SAE1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

SUMO1 activating enzyme subunit 1

Gene Aliases

AOS1, SUA1, UBLE1A, HSPC140

Gene ID

10055

Swiss Prot

Q9UBE0

Accession Number

NP_005491

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SAE1

Target

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]) .

Partner Proteins

FUS; USP39; SUMO2; HSPA2; HSPA1A; UBC; TRMT10A; DPP9; RPRD1B; NPLOC4; OSGEP; PANK4; WDR4; CUL5; TPD52L2; SRP14; RANGAP1; PPP2R5E; MCM3; LPP; DHPS; CALU; ADSL; AARS; PDE12; TP53RK; UBE2I; UBA2; BAG3; PTK2; IL3RA; APP; SUMO1; ETV4; BCL6; UBE2E3; SUMO3; SP10

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAE

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 92%; Rat: 100%; Yeast: 86%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

38kDa

Protein Length

346

NCBI Gene Symbol

SAE1

Host or Source

Rabbit

Protein Name

SUMO-activating enzyme subunit 1

Gene Name URL

SAE1

Nucleotide Accession Number

NM_005500

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