What is the catalog number for CENPB antibody - C-terminal region (ARP51969_P050)?

The catalog number for CENPB antibody - C-terminal region (ARP51969_P050) is ARP51969_P050.

What sizes are available for CENPB antibody - C-terminal region (ARP51969_P050)?

CENPB antibody - C-terminal region (ARP51969_P050) is available in the following size(s): 100 µL.

Is CENPB antibody - C-terminal region (ARP51969_P050) in stock?

CENPB antibody - C-terminal region (ARP51969_P050) is currently made to order / not held in immediate stock. Contact us for lead time.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

CENPB antibody - C-terminal region (ARP51969_P050)

Selected Variant

ARP51969_P050

Size: 100 µL

Product Specifications

CAS Number

9007-83-4

Gene Name

Centromere protein B, 80kDa

Gene ID

1059

Swiss Prot

P07199

Accession Number

NP_001801

Reactivity

Human, Mouse, Rat, Cow, Horse, Pig, Sheep, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CENPB

Target

CENPB is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

UBC; RNF2; NR3C1; FBXO25; CENPA; APP; GFI1B; SUMO2; SMN1; PIN1; GSK3B; GADD45A; CSNK2B; CDKN1A; ANXA7; RPS6KA6; TK1; TAC1; TAF1D; PARP1; PARP2; HAND2; CENPB

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEAMAYFAMVK

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 83%; Horse: 86%; Human: 100%; Mouse: 93%; Pig: 86%; Rat: 100%; Sheep: 86%; Yeast: 100%; Zebrafish: 75%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

65kDa

Protein Length

599

NCBI Gene Symbol

CENPB

Host or Source

Rabbit

Protein Name

Major centromere autoantigen B

Gene Name URL

CENPB

Nucleotide Accession Number

NM_001810

Price

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