GRK2 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

G protein-coupled receptor kinase 2

Gene Aliases

BARK1, ADRBK1, BETA-ARK1

Gene ID

156

Swiss Prot

P25098

Accession Number

NP_001610

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human ADRBK1

Target

This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease.

Partner Proteins

UBC; SUMO1; NEDD8; Rapgef3; GNAQ; FBXO25; ADRBK2; ACACA; HSP90AB1; HSP90AA1; GIT1; RASGRF1; MDM2; EPHA2; PEBP1; ADRB2; SNCA; GRM1; GNB1; KCNIP3; ARRB1; HDAC6; Nedd4; CSNK2B; PDGFRB; TPM2; GIT2; PDE6G; CCR4; AKAP12; PDCL; NCS1; MAPK3; PRKACA; CCR5; PIK3CG

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPRSPVVELSKVPL

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol