EIF2B1 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa

Gene Aliases

EIF2B, EIF2BA

Gene ID

1967

Swiss Prot

Q14232

Accession Number

NP_001405

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human EIF2B1

Target

EIF2B1 belongs to the EIF-2B alpha/beta/delta subunits family. It catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Defects in EIF2B1 are a cause of leukoencephalopathy with vanishing white matter (VWM) .

Partner Proteins

RD3; WDYHV1; GORASP2; EIF2B1; UBC; GCD2; GCD6; EIF2B2; STK11; DCC; MRPL4; EIF2S2; EIF2S1; ARL4D; CREBBP; ADRB2; ADRA2B; ADRA2C; ADRA2A; EIF2B5; DCD; PDIA4; EIF2B3; HNRNPL; ARHGDIA

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ADTLKVAQTGQDLKEEHPWVDYTAPSLITLLFTDLGVLTPSAVSDELIKL

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 79%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 79%; Rabbit: 79%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

34kDa

Protein Length

305

NCBI Gene Symbol

EIF2B1

Host or Source

Rabbit

Protein Name

Translation initiation factor eIF-2B subunit alpha

Gene Name URL

EIF2B1

Nucleotide Accession Number

NM_001414

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